Murray: Medical Microbiology, 6^th Edition

Chapter 6: Viral Classification, Structure, and Replication

MULTIPLE CHOICE

1. Herpes simplex virus was genetically engineered as a gene delivery vehicle. Insertion of the new gene into which of the viral genes would prevent replication of the virus in all cells?

ANS: A

1. An outbreak of gastroenteritis occurred on a cruise ship. A stool sample from one of the passengers contained a very small detergent-resistant virus. What other parameter would be true for this virus?

ANS: E

1. A 34-year-old woman is jaundiced, has fever and nausea, lacks appetite, and has abdominal pain. She claims that the disease signs started 3 days earlier. A stool sample contained a small detergent-resistant virus. Which of the following describes a likely consequence of this infection?

ANS: C

1. A 34-year-old woman has been feeling very tired for several months and blood tests showed elevated levels of liver enzymes. A blood sample tested positive for viral antigen and RNA for a +RNA virus, but no virus could be isolated or seen in this or other samples. Which of the following describes the most likely consequence of this infection?

ANS: B

1. A 3-year-old child has a group of lesions that include vesicles, crusted vesicles, and ulcers around the corner of his mouth. A Tzanck smear shows Cowdry type A inclusion bodies. Which is the most appropriate description for this microbe?

ANS: C

Murray: Medical Microbiology, 6^th Edition

Chapter 09: Elements of Host Protective Responses

Test Bank

MULTIPLE CHOICE

1. How can a Bell cell be distinguished from a T cell?

ANS: B

1. Which cell type would not be present in a boy born without a thymus?

ANS: C

1. Which cell type produces acute-phase cytokines?

ANS: D

1. A ruptured spleen was removed from a 37-year-old car accident victim. What would be the consequence?

ANS: E

1. Soon after HIV infection, the gut becomes smooth due to the loss of MALT. Loss of the MALT will compromise the production of which type of antibody?

ANS: A

1. A blood count from a 6-year-old boy with fever is reported to have undergone “a left shift with an increase in bands.” This refers to an increase in:

ANS: C

Murray: Medical Microbiology, 6^th Edition

Chapter 13: Antimicrobial Vaccines

Test Bank

MULTIPLE CHOICE

1. Which of the following responses would be elicited by vaccination with Jeryl Lynn mumps vaccine but not with the hepatitis B vaccine?

ANS: B

1. The Gates Foundation is interested in funding the development of a new vaccine for measles. Which of the following advantages should the improved vaccine have over the current vaccine?

ANS: B

1. Why is the inactivated polio vaccine (IPV) recommended in the United States instead of the oral live attenuated vaccine (OPV) for routine immunizations?
2. IPV initiates lifelong immune response.
3. IPV promotes Herd immunity.
4. Smaller amounts of the IPV are required.
5. IPV cannot cause disease.
6. IPV is easier to administer to children.

ANS: D

1. Match the following questions with the appropriate description for the currently used vaccines. (Choose all that apply.)
2. Live attenuated microbe
3. Inactivated microbe
4. Subunit (protein)
5. polysaccharide
6. conjugated polysaccharide
7. A & B
8. D & E

1. Haemophilus influenzae B
2. Streptococcus pneumoniae
3. Mumps
4. Varicella zoster
5. Influenza
6. Diphtheria
7. Tetanus
8. Bordetella pertussis
9. Hepatitis B
10. Hepatitis A
11. Rotavirus

ANS: 4. E

1. D, E
2. A
3. A
4. A, B
5. C
6. C
7. C
8. C
9. C
10. A

1. A four-year-old child is bitten by a raccoon kitten. Unfortunately the animal has escaped. Which of the following actions should be taken?

1. Wash the wound carefully, and treat the child with a 2-week course of vancomycin.
2. Wash the wound carefully, infuse the area with rabies gamma globulin, and initiate live vaccine immunization.
3. Wash the wound carefully, infuse the area with rabies gamma globulin, and initiate inactivated vaccine immunization.

ANS: C

1. What action will the rabies gamma globulin have?
2. Initiate B-cell production of antibody.
3. Activate T cells.
4. Facilitate virus clearance by macrophages.
5. Promote virus clearance by neutrophils.
6. Block virus spread by T cells.

ANS: C